Fatal subacute cytomegalovirus encephalitis associated with hypogammaglobulinemia and thymoma

May 22nd, 2008 by admin

From:

Mayo Clinic Proceedings

Date:

February 1, 2003

Author:

Forman, Mark S; Kasner, Scott E; King, David; McGarvey, Michael L; Cucchiara, Brett L

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Thymoma | Copyright information Copyright Mayo Foundation for Medical Education and Research Feb 2003. This material is published under license from the publisher through ProQuest Information and Learning Company, Ann Arbor, Michigan. All inquiries regarding rights should be directed to ProQuest Information and Learning Company.

Parathymic syndromes are systemic disorders that occur in association with thymoma. One such parathymic syndrome, hypogammaglobulinemia, was initially identified by Good in 1954 and has been referred to as Good syndrome. Patients with this syndrome develop a variety of recurrent infections due to the associated immunodeficiency. We describe a patient with cytomegalovirus encephalitis associated with Good syndrome and discuss the pathologic findings present on autopsy. The possibility of a

cytomegalovirus infection should be considered early in the evaluation of patients with Good syndrome if appropriate clinical symptoms are present

Mayo Clin Proc. 2003;78:223-227

CMV = cytomegalovirus; …

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